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Know-how & Expertises

Probiotics contract-manufacturer

True synergistic skills

Probiotics are living microorganisms, which, when administrated in adequate amounts, confer a health benefit on the host. (FAO/WHO 2001)

Selection and objectivation of probiotic strains.

Manufacturing and packaging of finished product.

Synergistic expert skills dedicated to your probiotic product.

Strain selection

In order to provide, safe, stable and efficient probiotic products, GENIBIO has settled a rigorous screening procedure of available food grade microorganisms system with a large range of tests and controls at each step, from research up to finished product:

Identification and safety

Strain supplier guarantees on a contractual basis with GENIBIO the precise taxonomy, purity and identity over time. Selected strains are commonly used in food industry and they are totally safe for human consumption (QPS updated list of EFSA).

Ageing studies

Viability tests are performed to guarantee bacterial population from one billion or more per dose and per strain in the finished product. Strains could be spoiled during process and storage. To obtain a high-end finished product, it is essential to maintain the high number of viable cells necessary for the in vivo probiotic effect during the storage. Stability of probiotics is tested in various conditions of temperature and hygrometry. Optimized formulations are stable at least 2 years at ambient temperature.

In vitro objectivation studies

In collaboration with expert public research teams, GENIBIO has validated a range of in vitro tests for the evaluation of probiotic potential of industrial lactic acid bacteria and bifidobacteria strains: survival rate in gastroduodenal models, production of antimicrobial substances, adhesion to intestinal or vaginal mucosa and immunomodulation properties.

Formulation

In partnership with PiLeJe Industrie, GENIBIO develops original formulations associating one or more selected strains and other active components having synergistic effects with probiotic strains (prebiotics, trace elements, vitamins and plant extracts), in accordance with your requirements. Specific formulae can also be developed including non-digestible food ingredients which promote survival and growth of beneficial bacteria in the human intestinal tract.

Production

GENIBIO produces the bulk mixes of the tailor-made formula developed and collaborates strongly with PiLeJe Industrie to insure high-quality finished products to their common customers. GENIBIO has developed a rigorous and complete quality system according to ISO 9001, and a food safety system based on a HACCP approach according to ISO 22000, to provide safe and efficient formula with long shelf-life before consumption.
SpeciesOrigin
Bifidobacterium bifidumHuman
Bifidobacterium bifidumHuman
Bifidobacterium breveHuman
Bifidobacterium infantisHuman
Bifidobacterium animalis ssp lactisHuman
Bifidobacterium animalis ssp lactisHuman
Bifidobacterium longumDairy
Lactobacillus acidophilusHuman
Lactobacillus acidophilusHuman
Lactobacillus acidophilusHuman
Lactobacillus caseiDairy
Lactobacillus caseiHuman
SpeciesOrigin
Lactobacillus gasseriHuman
Lactobacillus helveticusHuman
Lactobacillus paracaseiHuman
Lactobacillus paracaseiHuman
Lactobacillus plantarumVegetal
Lactobacillus plantarumDairy
Lactobacillus rhamnosusHuman
Lactobacillus rhamnosusHuman
Lactobacillus salivariusUnkown
Lactococcus lactisUnkown
Streptococcus thermophilusDairy
Saccharomyces cerevisiae var. boulardiiVegetal

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